Version 5.4
Mus musculus Protein: Eif4e1b
Summary
InnateDB Protein IDBP-261190.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif4e1b
Protein Name eukaryotic translation initiation factor 4E family member 1B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000105630
InnateDB Gene IDBG-154342 (Eif4e1b)
Protein Structure
UniProt Annotation
Function Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005845 mRNA cap binding complex
Protein Structure and Domains
PDB ID MGI:2685119
InterPro IPR001040 Translation Initiation factor eIF- 4e
IPR023398 Translation Initiation factor eIF- 4e-like domain
PFAM PF01652
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UTA9
PhosphoSite PhosphoSite-
TrEMBL Q27ZJ0
UniProt Splice Variant
Entrez Gene 218268
UniGene Mm.425821
RefSeq
MGI ID
MGI Symbol Eif4e1b
OMIM
CCDS CCDS49269
HPRD
IMGT
EMBL AC162526 AK139577 BC139143 BC139144 DQ279473 DQ279474 DQ279475
GenPept AAI39144 AAI39145 ABB88894 ABB88895 ABB88896 BAE24071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca