InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tcn2

Summary

InnateDB Protein

IDBP-261217.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tcn2

Protein Name

transcobalamin 2

Synonyms

AW208754; Tcn-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105617

InnateDB Gene

IDBG-141204 (Tcn2)

Protein Structure

UniProt Annotation

Function

Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0031419	cobalamin binding
GO:0046872	metal ion binding

Biological Process

GO:0006824	cobalt ion transport
GO:0009235	cobalamin metabolic process
GO:0015889	cobalamin transport

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

MGI:98534

InterPro

IPR002157 Cobalamin (vitamin B12)-binding transporter, eukaryotic
IPR019554 Soluble ligand binding domain

PFAM

PF01122
PF10531

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O88968

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

21452

UniGene

Mm.20948

RefSeq

NP_001123931

MGI ID

MGI Symbol

Tcn2

OMIM

CCDS

CCDS24371

HPRD

IMGT

EMBL

AF090686 AK133707 AK143761 AK147176 AK161618 AK170401 AL807241 AL807395 BC003720 CH466574

GenPept

AAC61868 AAH03720 BAE21792 BAE25528 BAE27739 BAE36496 BAE41770 CAI26040 CAI51997 EDL40449