Version 5.4
Mus musculus Protein: Clmn
Summary
InnateDB Protein IDBP-261318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clmn
Protein Name calmin
Synonyms 9330188N17Rik; AI428889; AI788815; mKIAA1188;
Species Mus musculus
Ensembl Protein ENSMUSP00000105563
InnateDB Gene IDBG-168594 (Clmn)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Isoform 1: Membrane {ECO:0000305}; Single- pass type IV membrane protein {ECO:0000305}. Note=Shows a reticular pattern in the cytoplasm.Isoform 4: Membrane {ECO:0000305}; Single- pass type IV membrane protein {ECO:0000305}. Note=Shows a reticular pattern in the cytoplasm.Isoform 2: Cytoplasm.Isoform 3: Cytoplasm.
Disease Associations
Tissue Specificity Expressed in testis. Expressed during testis maturation process and in maturing spermatids. In brain, it is expressed in neurons of the hippocampus, cerebral cortex, and thalamus, Purkinje cells, and also in the choroid plexus and ependymal cells. Expressed predominantly in dendrites and cell bodies of the neurons, but not in axons. The level of expression increases during the period of maturation of the mouse brain after birth. {ECO:0000269PubMed:11386753, ECO:0000269PubMed:12670712}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0031175 neuron projection development
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2136957
InterPro IPR001715 Calponin homology domain
PFAM PF00307
PRINTS
PIRSF
SMART SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C5W0
PhosphoSite PhosphoSite-Q8C5W0
TrEMBL
UniProt Splice Variant
Entrez Gene 94040
UniGene Mm.474939
RefSeq NP_444385
MGI ID
MGI Symbol Clmn
OMIM
CCDS CCDS36541
HPRD
IMGT
EMBL AB047978 AB059643 AB059644 AB059645 AB059646 AB059647 AB059648 AK077023
GenPept BAB59009 BAB59120 BAB59121 BAB59122 BAB59123 BAB59124 BAB59125 BAC36573

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca