InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ascc2

Summary

InnateDB Protein

IDBP-261338.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ascc2

Protein Name

activating signal cointegrator 1 complex subunit 2

Synonyms

1700011I11Rik; 2610034L15Rik; AI482016; ASC1p100; AW046480;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105556

InnateDB Gene

IDBG-142720 (Ascc2)

Protein Structure

UniProt Annotation

Function

Enhances NF-kappa-B, SRF and AP1 transactivation. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008150	biological_process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1922702

InterPro

IPR003892 Ubiquitin system component Cue
IPR009060 UBA-like

PFAM

PF02845

PRINTS

PIRSF

SMART

SM00546

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91WR3

PhosphoSite

PhosphoSite-Q91WR3

TrEMBL

Q9CVZ2

UniProt Splice Variant

Entrez Gene

75452

UniGene

Mm.439906

RefSeq

MGI ID

MGI Symbol

Ascc2

OMIM

CCDS

HPRD

IMGT

EMBL

AK005869 AK048876 AK051387 AL606521 BC013537 BC024840

GenPept

AAH13537 AAH24840 BAB24289 BAC33480 BAC34621 CAI35279