InnateDB Protein
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IDBP-261340.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tmem90b
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Protein Name
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transmembrane protein 90B
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000105561
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InnateDB Gene
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IDBG-209207 (Tmem90b)
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Protein Structure
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Function |
May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation. {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:20152115}; Single-pass type II membrane protein {ECO:0000269PubMed:20152115}. Early endosome membrane {ECO:0000269PubMed:20152115}; Single-pass type II membrane protein {ECO:0000269PubMed:20152115}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000269PubMed:20152115}. Cell junction, synapse {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=Shuttles between the cell surface and early endosome membrane.
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Disease Associations |
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Tissue Specificity |
Brain-specific. Expressed in Purkinje neurons in cerebellum. Also detected in the hippocampus. Found at excitatory synapses and postsynaptic cells. {ECO:0000269PubMed:12408845, ECO:0000269PubMed:20152115}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0035254
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glutamate receptor binding
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GO:0042803
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protein homodimerization activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:3702158
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InterPro |
IPR007593
CD225/Dispanin family
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PFAM |
PF04505
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A2ANU3
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PhosphoSite |
PhosphoSite-AAI47353
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TrEMBL |
B1AYD6
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UniProt Splice Variant |
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Entrez Gene |
433485
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UniGene |
Mm.445136
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RefSeq |
NP_001078990
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MGI ID |
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MGI Symbol |
Syndig1
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OMIM |
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CCDS |
CCDS38262
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HPRD |
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IMGT |
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EMBL |
AL831742
AL845436
BC147352
BC147353
BC147660
BC147661
BX649512
CH466519
CR388226
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GenPept |
AAI47353
AAI47354
AAI47661
AAI47662
CAM13941
CAM20081
EDL28557
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