InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SAT2

Summary

InnateDB Protein

IDBP-26150.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SAT2

Protein Name

spermidine/spermine N1-acetyltransferase family member 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000269298

InnateDB Gene

IDBG-26146 (SAT2)

Protein Structure

UniProt Annotation

Function

Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine.

Subcellular Localization

Cytoplasm. Note=Intracellular organelles.

Disease Associations

Tissue Specificity

Widely expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004145	diamine N-acetyltransferase activity
GO:0008080	N-acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0009447	putrescine catabolic process
GO:0032918	spermidine acetylation
GO:0032919	spermine acetylation
GO:0032920	putrescine acetylation
GO:0046204	nor-spermidine metabolic process