Version 5.4
Mus musculus Protein: Zmiz2
Summary
InnateDB Protein IDBP-261639.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zmiz2
Protein Name zinc finger, MIZ-type containing 2
Synonyms Zimp7;
Species Mus musculus
Ensembl Protein ENSMUSP00000105409
InnateDB Gene IDBG-147533 (Zmiz2)
Protein Structure
UniProt Annotation
Function Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Detected at replication foci throughout S phase. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0043596 nuclear replication fork
Protein Structure and Domains
PDB ID MGI:106374
InterPro IPR004181 Zinc finger, MIZ-type
PFAM PF02891
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CIE2
PhosphoSite PhosphoSite-Q8CIE2
TrEMBL
UniProt Splice Variant
Entrez Gene 52915
UniGene Mm.409630
RefSeq XP_006514811
MGI ID
MGI Symbol Zmiz2
OMIM
CCDS CCDS24418
HPRD
IMGT
EMBL AK048533 AL607152 BC024081 BC060652 BC063069
GenPept AAH24081 AAH60652 AAH63069 BAC33364 CAI24407 CAI24408 CAI24409

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca