InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdk5rap1

Summary

InnateDB Protein

IDBP-261764.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdk5rap1

Protein Name

CDK5 regulatory subunit associated protein 1

Synonyms

2310066P17Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105353

InnateDB Gene

IDBG-210354 (Cdk5rap1)

Protein Structure

UniProt Annotation

Function

Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0016740	transferase activity
GO:0032403	protein complex binding
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

Biological Process

GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006400	tRNA modification
GO:0009451	RNA modification
GO:0043412	macromolecule modification
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1914221

InterPro

IPR002792 TRAM domain
IPR005839 Methylthiotransferase
IPR006638 Elongator protein 3/MiaB/NifB
IPR007197 Radical SAM
IPR013848 Methylthiotransferase, N-terminal

PFAM

PF01938
PF04055
PF00919

PRINTS

PIRSF

SMART

SM00729

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BTW8