Version 5.4
Mus musculus Protein: Dlgap4
Summary
InnateDB Protein IDBP-262120.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlgap4
Protein Name discs, large homolog-associated protein 4 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000105195
InnateDB Gene IDBG-210957 (Dlgap4)
Protein Structure
UniProt Annotation
Function May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007267 cell-cell signaling
GO:0008150 biological_process
Cellular Component
GO:0016020 membrane
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:2138865
InterPro IPR005026 Guanylate-kinase-associated protein
PFAM PF03359
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B1AZP2
PhosphoSite PhosphoSite-B1AZP2
TrEMBL H3BL90
UniProt Splice Variant
Entrez Gene 228836
UniGene Mm.413994
RefSeq NP_001264115
MGI ID
MGI Symbol Dlgap4
OMIM
CCDS CCDS71171
HPRD
IMGT
EMBL AK122408 AY243849 BC024558 BC058948 BC085475 BC106094 BC141110 BC145394 BX004793 BX571766
GenPept AAH24558 AAH58948 AAH85475 AAI06095 AAI41111 AAI45395 AAO89220 BAC65690 CAM16917 CAM16918 CAM16919 CAM22345 CAM22346 CAM22347

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca