InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Polr2c

Summary

InnateDB Protein

IDBP-262216.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Polr2c

Protein Name

polymerase (RNA) II (DNA directed) polypeptide C

Synonyms

33kDa; mRBP31; RPB3; Rpo2-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105147

InnateDB Gene

IDBG-182817 (Polr2c)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 80 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	80 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001055	RNA polymerase II activity
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005665	DNA-directed RNA polymerase II, core complex
GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton

Protein Structure and Domains

PDB ID

MGI:109299

InterPro

IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain
IPR011262 DNA-directed RNA polymerase, insert domain
IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type

PFAM

PF01193
PF01000

PRINTS

PIRSF

SMART

SM00662

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite