InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP1B2

Summary

InnateDB Protein

IDBP-26304.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP1B2

Protein Name

ATPase, Na+/K+ transporting, beta 2 polypeptide

Synonyms

AMOG;

Species

Homo sapiens

Ensembl Protein

ENSP00000250111

InnateDB Gene

IDBG-26302 (ATP1B2)

Protein Structure

UniProt Annotation

Function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth. {ECO:0000250}.

Subcellular Localization

Cell membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005391	sodium:potassium-exchanging ATPase activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006813	potassium ion transport
GO:0006814	sodium ion transport
GO:0007155	cell adhesion
GO:0007596	blood coagulation
GO:0034220	ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0050900	leukocyte migration
GO:0055085	transmembrane transport