InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Irgm2

Summary

InnateDB Protein

IDBP-263695.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Irgm2

Protein Name

immunity-related GTPase family M member 2

Synonyms

AI481100; GTPI; Ifggd2; Iigp2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104464

InnateDB Gene

IDBG-176361 (Irgm2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0016817	hydrolase activity, acting on acid anhydrides

Biological Process

GO:0006184	GTP catabolic process
GO:0034341	response to interferon-gamma
GO:0042742	defense response to bacterium
GO:0042832	defense response to protozoan

Cellular Component

GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0020003	symbiont-containing vacuole

Protein Structure and Domains

PDB ID

MGI:1926262

InterPro

IPR007743 Interferon-inducible GTPase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF05049

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-Q9Z1M2

TrEMBL

Q9Z1M2

UniProt Splice Variant

Entrez Gene

54396

UniGene

Mm.458517

RefSeq

NP_062313

MGI ID

MGI Symbol

Irgm2

OMIM

CCDS

CCDS48803

HPRD

IMGT

EMBL

AJ007972 AK142291 AL928857 FR734033

GenPept

BAE25015 CAA07799 CBY65996