Version 5.4
Mus musculus Protein: Dnajc5
Summary
InnateDB Protein IDBP-263771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnajc5
Protein Name DnaJ (Hsp40) homolog, subfamily C, member 5
Synonyms 2610314I24Rik; AU018536; Csp;
Species Mus musculus
Ensembl Protein ENSMUSP00000104425
InnateDB Gene IDBG-214134 (Dnajc5)
Protein Structure
UniProt Annotation
Function May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000269PubMed:17034881}; Lipid-anchor {ECO:0000269PubMed:17034881}. Melanosome {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with insulin granules, when overexpressed in a islet cell line.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0043008 ATP-dependent protein binding
Biological Process
GO:0043524 negative regulation of neuron apoptotic process
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0042470 melanosome
Protein Structure and Domains
PDB ID MGI:892995
InterPro IPR001623 DnaJ domain
PFAM PF00226
PRINTS PR00625
PIRSF
SMART SM00271
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60904
PhosphoSite PhosphoSite-P60904
TrEMBL A2AUE1
UniProt Splice Variant
Entrez Gene 13002
UniGene Mm.408969
RefSeq
MGI ID 2CTW
MGI Symbol Dnajc5
OMIM
CCDS CCDS17215
HPRD
IMGT
EMBL AF032115 AK029006 AK032373 AL929094
GenPept AAB87080 BAC26236 BAC27841

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca