Homo sapiens Protein: GK2
Summary
InnateDB Protein IDBP-26379.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GK2
Protein Name glycerol kinase 2
Synonyms GKP2; GKTA;
Species Homo sapiens
Ensembl Protein ENSP00000351706
InnateDB Gene IDBG-26377 (GK2)
Protein Structure
UniProt Annotation
Function Key enzyme in the regulation of glycerol uptake and metabolism. {ECO:0000250}.
Subcellular Localization Mitochondrion outer membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In sperm the majority of the enzyme is bound to mitochondria. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004370 glycerol kinase activity
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0016310 phosphorylation
GO:0019563 glycerol catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR005999 Glycerol kinase
IPR018484 Carbohydrate kinase, FGGY, N-terminal
IPR018485 Carbohydrate kinase, FGGY, C-terminal
PFAM PF00370
PF02782
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14410
PhosphoSite PhosphoSite-Q14410
TrEMBL
UniProt Splice Variant
Entrez Gene 2712
UniGene Hs.98008
RefSeq NP_149991
HUGO HGNC:4291
OMIM
CCDS CCDS3585
HPRD 15966
IMGT
EMBL AK292241 BC029820 BC048274 BC058888 CH471057 X78712
GenPept AAH29820 AAH48274 AAH58888 BAF84930 CAA55365 EAX05842