Version 5.4
Mus musculus Protein: Neurl4
Summary
InnateDB Protein IDBP-264149.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neurl4
Protein Name neuralized homolog 4 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000104257
InnateDB Gene IDBG-192580 (Neurl4)
Protein Structure
UniProt Annotation
Function Promotes CCP110 ubiquitination and proteasome-dependent degradation. By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing formation of ectopic microtubular organizing centers (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005814 centriole
Protein Structure and Domains
PDB ID MGI:1921092
InterPro IPR006573 NEUZ
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF07177
PRINTS
PIRSF
SMART SM00588
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5NCX5
PhosphoSite PhosphoSite-Q5NCX5
TrEMBL Q80YV0
UniProt Splice Variant
Entrez Gene 216860
UniGene Mm.420336
RefSeq
MGI ID
MGI Symbol Neurl4
OMIM
CCDS
HPRD
IMGT
EMBL AK157107 AK173264 AL596185 BC023037 BC050154 BC058434
GenPept AAH23037 AAH50154 AAH58434 BAD32542 BAE33965 CAI35149 CAI35150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca