Version 5.4
Mus musculus Protein: Gp1ba
Summary
InnateDB Protein IDBP-264295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gp1ba
Protein Name glycoprotein 1b, alpha polypeptide
Synonyms GPIba; GPIbalpha;
Species Mus musculus
Ensembl Protein ENSMUSP00000104191
InnateDB Gene IDBG-195005 (Gp1ba)
Protein Structure
UniProt Annotation
Function GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. {ECO:0000250}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0007155 cell adhesion
GO:0007596 blood coagulation
GO:0007599 hemostasis
GO:0042730 fibrinolysis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0031362 anchored component of external side of plasma membrane
Protein Structure and Domains
PDB ID MGI:1333744
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01463
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00082
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35930
PhosphoSite PhosphoSite-O35930
TrEMBL A2CFB8
UniProt Splice Variant
Entrez Gene 14723
UniGene Mm.377085
RefSeq
MGI ID 1K15
MGI Symbol Gp1ba
OMIM
CCDS CCDS24957
HPRD
IMGT
EMBL AL596117 BC137765 CH466596 U91967
GenPept AAC53320 AAI37766 CAI25162 EDL12587

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca