InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HBG1

Summary

InnateDB Protein

IDBP-26437.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HBG1

Protein Name

hemoglobin, gamma A

Synonyms

HBG-T2; HBGA; HBGR; HSGGL1;

Species

Homo sapiens

Ensembl Protein

ENSP00000327431

InnateDB Gene

IDBG-236512 (HBG1)

Protein Structure

UniProt Annotation

Function

Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.

Subcellular Localization

Disease Associations

Tissue Specificity

Red blood cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005344	oxygen transporter activity
GO:0005506	iron ion binding
GO:0019825	oxygen binding
GO:0020037	heme binding

Biological Process

GO:0007596	blood coagulation
GO:0015671	oxygen transport

Cellular Component

GO:0005829	cytosol
GO:0005833	hemoglobin complex

Protein Structure and Domains

PDB ID

InterPro

IPR000971 Globin
IPR002335 Myoglobin
IPR002337 Haemoglobin, beta
IPR009050 Globin-like

PFAM

PF00042

PRINTS

PR00613
PR00814

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P69891

PhosphoSite

PhosphoSite-P69891

TrEMBL

D9YZU8

UniProt Splice Variant

Entrez Gene

3047

UniGene

RefSeq

NP_000550

HUGO

HGNC:4831

OMIM

142200

CCDS

CCDS7754

HPRD

00789

IMGT

EMBL

AF130098 AF487523 BC010913 BC020719 CH471064 GU324925 J00176 M91036 M91037 U01317 V00513 V00514

GenPept

AAA16332 AAA52637 AAA58493 AAB59429 AAG35523 AAH10913 AAH20719 AAL99545 ADL14496 CAA23771 CAA23772 EAW68804