InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zfp541

Summary

InnateDB Protein

IDBP-264392.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zfp541

Protein Name

zinc finger protein 541

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104149

InnateDB Gene

IDBG-264390 (Zfp541)

Protein Structure

UniProt Annotation

Function

Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. {ECO:0000269PubMed:18849567}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00512, ECO:0000255PROSITE-ProRule:PRU00624, ECO:0000269PubMed:17662146, ECO:0000269PubMed:18849567}.

Disease Associations

Tissue Specificity

Germ-cell-specific. Specifically present in testicular spermatogenic cells, but not in testicular and mature sperm. During spermatogenesis, it is present in spermatocytes and round spermatids only (at protein level). {ECO:0000269PubMed:17662146, ECO:0000269PubMed:18849567}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0008150	biological_process
GO:0030154	cell differentiation