InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rtn2

Summary

InnateDB Protein

IDBP-264473.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rtn2

Protein Name

reticulon 2 (Z-band associated protein)

Synonyms

MMS10-P; Ms10p; Nspl1; NSPLI;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104108

InnateDB Gene

IDBG-150051 (Rtn2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed predominantly in neural and muscular tissues. {ECO:0000269PubMed:9530622}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0046324	regulation of glucose import
GO:0065002	intracellular protein transmembrane transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0014802	terminal cisterna
GO:0016021	integral component of membrane
GO:0030315	T-tubule

Protein Structure and Domains

PDB ID

MGI:107612

InterPro

IPR003388 Reticulon

PFAM

PF02453

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O70622

PhosphoSite

PhosphoSite-O70622

TrEMBL

Q6IM74

UniProt Splice Variant

Entrez Gene

20167

UniGene

RefSeq

NP_001020535

MGI ID

MGI Symbol

Rtn2

OMIM

CCDS

CCDS39797

HPRD

IMGT

EMBL

AF038537 AF038538 AF038539 AF093624 BC031370 BK001790

GenPept

AAC14906 AAC14907 AAC14908 AAC14909 AAD13195 AAH31370 DAA01963