InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gsk3a

Summary

InnateDB Protein

IDBP-264593.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Gsk3a

Protein Name

glycogen synthase kinase 3 alpha

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104049

InnateDB Gene

IDBG-156635 (Gsk3a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0016477	cell migration
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0071285	cellular response to lithium ion
GO:0071407	cellular response to organic cyclic compound

Cellular Component

Protein Structure and Domains

PDB ID

MGI:2152453

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt