Version 5.4
Mus musculus Protein: B9d2
Summary
InnateDB Protein IDBP-264610.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B9d2
Protein Name B9 protein domain 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000104040
InnateDB Gene IDBG-158255 (B9d2)
Protein Structure
UniProt Annotation
Function Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. {ECO:0000269PubMed:18287022, ECO:0000269PubMed:22179047}.
Subcellular Localization Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269PubMed:18287022}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269PubMed:18287022}. Nucleus {ECO:0000269PubMed:18287022}.
Disease Associations
Tissue Specificity Highest expression in thymus and skeletal muscle. Also expressed in spleen, kidney, lung, heart, microglia and liver. Detected in brain (at protein level). {ECO:0000269PubMed:18287022}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043015 gamma-tubulin binding
Biological Process
GO:0042384 cilium assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0016020 membrane
GO:0036038 TCTN-B9D complex
GO:0036064 ciliary basal body
Protein Structure and Domains
PDB ID MGI:2387643
InterPro IPR010796 B9 domain
PFAM PF07162
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UK10
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 232987
UniGene
RefSeq NP_742160
MGI ID
MGI Symbol B9d2
OMIM
CCDS CCDS20992
HPRD
IMGT
EMBL AK141500 AK146227 BC028440
GenPept AAH28440 BAE24704 BAE26994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca