Mus musculus Protein: Fbxo17
Summary
InnateDB Protein IDBP-264880.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo17
Protein Name F-box protein 17
Synonyms Fbg4; Fbx17; Fbxo26;
Species Mus musculus
Ensembl Protein ENSMUSP00000103913
InnateDB Gene IDBG-164035 (Fbxo17)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed primarily in the brain. {ECO:0000269PubMed:18203720}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Protein Structure and Domains
PDB ID MGI:1354707
InterPro IPR001810 F-box domain
IPR007397 F-box associated (FBA) domain
IPR008979 Galactose-binding domain-like
PFAM PF00646
PF12937
PF13013
PF04300
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZM8
PhosphoSite PhosphoSite-
TrEMBL Q3V064
UniProt Splice Variant
Entrez Gene 50760
UniGene Mm.358659
RefSeq
MGI ID
MGI Symbol Fbxo17
OMIM
CCDS CCDS39863
HPRD
IMGT
EMBL AF176532 AK133408 BC026470 CH466593
GenPept AAF09141 AAH26470 BAE21641 EDL24123