Version 5.4
Mus musculus Protein: Necab1
Summary
InnateDB Protein IDBP-264888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Necab1
Protein Name N-terminal EF-hand calcium binding protein 1
Synonyms 1700003H21Rik; Efcbp1; STIP-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000103908
InnateDB Gene IDBG-130377 (Necab1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:12044471}.
Disease Associations
Tissue Specificity Expressed in brain (at protein level). Expressed in the cerebral cortex only in layer 4, thalamic nuclei (the mediodorsal nucleus), hippocampus (a small band of pyramidal neurons at the boundary between CA1 and CA3), interneurons interspersed throughout the hippocampus proper, interneurons in the hilus, bodies of the neurons but also their dendritic projections (at protein level). {ECO:0000269PubMed:12044471}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1916602
InterPro IPR002048 EF-hand domain
IPR007138 Antibiotic biosynthesis monooxygenase
IPR011008 Dimeric alpha-beta barrel
PFAM PF00036
PF13202
PF13405
PF03992
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BG18
PhosphoSite PhosphoSite-Q8BG18
TrEMBL
UniProt Splice Variant
Entrez Gene 69352
UniGene Mm.403781
RefSeq
MGI ID
MGI Symbol Necab1
OMIM
CCDS CCDS17982
HPRD
IMGT
EMBL AK039240 AK050307 AK081951 AL732571 AL831792 AL929383 AY278200 BC067055
GenPept AAH67055 AAP32077 BAC30290 BAC34179 BAC38379 CAM18343 CAM20237 CAM22572

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca