InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ksr1

Summary

InnateDB Protein

IDBP-264900.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ksr1

Protein Name

kinase suppressor of ras 1

Synonyms

AW492498; B-KSR1; D11Bhm183e; D11Bhm184e; hb; Ksr; RSU2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103899

InnateDB Gene

IDBG-203299 (Ksr1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 65 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	65 [view]
Protein-Protein	65 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005078	MAP-kinase scaffold activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0046872	metal ion binding

Biological Process

GO:0006468	protein phosphorylation
GO:0035556	intracellular signal transduction
GO:0043410	positive regulation of MAPK cascade

Cellular Component

Protein Structure and Domains

PDB ID

MGI:105051

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714
PF00130

PRINTS

PR00109

PIRSF

SMART

SM00109

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5SXE4

UniProt Splice Variant

Entrez Gene

16706

UniGene

Mm.397247

RefSeq

MGI ID

MGI Symbol

Ksr1

OMIM

CCDS

HPRD

IMGT

EMBL

AL592551

GenPept