InnateDB Protein
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IDBP-264970.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Spint2
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Protein Name
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serine protease inhibitor, Kunitz type 2
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Synonyms
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AL024025; C76321; HAI-2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000103871
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InnateDB Gene
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IDBG-166689 (Spint2)
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Protein Structure
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Function |
Inhibitor of HGF activator.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Isoform 2 is more predominantly expressed than isoform 1.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004867
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serine-type endopeptidase inhibitor activity
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Biological Process |
GO:0010951
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negative regulation of endopeptidase activity
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Cellular Component |
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PDB ID |
MGI:1338031
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InterPro |
IPR002223
Proteinase inhibitor I2, Kunitz metazoa
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PFAM |
PF00014
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PRINTS |
PR00759
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PIRSF |
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SMART |
SM00131
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TIGRFAMs |
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Modification |
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SwissProt |
Q9WU03
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PhosphoSite |
PhosphoSite-Q9WU03
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
20733
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UniGene |
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RefSeq |
NP_001076017
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MGI ID |
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MGI Symbol |
Spint2
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OMIM |
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CCDS |
CCDS39869
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HPRD |
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IMGT |
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EMBL |
AF099016
AF099019
AF099020
BC003431
BC026419
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GenPept |
AAD22172
AAD22173
AAD22174
AAH03431
AAH26419
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