InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pex5l

Summary

InnateDB Protein

IDBP-264988.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pex5l

Protein Name

peroxisomal biogenesis factor 5-like

Synonyms

1700016J08Rik; Pex2; PXR2; TRIP8b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103856

InnateDB Gene

IDBG-137344 (Pex5l)

Protein Structure

UniProt Annotation

Function

Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. {ECO:0000269PubMed:22550182}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Some fraction is membrane associated via its interaction with RAB8B. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005052	peroxisome matrix targeting signal-1 binding
GO:0005515	protein binding

Biological Process

GO:0016558	protein import into peroxisome matrix
GO:0016560	protein import into peroxisome matrix, docking
GO:0042391	regulation of membrane potential
GO:0043949	regulation of cAMP-mediated signaling
GO:0045185	maintenance of protein location