Version 5.4
Mus musculus Protein: Fut9
Summary
InnateDB Protein IDBP-265045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fut9
Protein Name fucosyltransferase 9
Synonyms AI746471; AU067636; mFuc-TIX; mFUT9;
Species Mus musculus
Ensembl Protein ENSMUSP00000103834
InnateDB Gene IDBG-132653 (Fut9)
Protein Structure
UniProt Annotation
Function Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. {ECO:0000269PubMed:9756916}.
Subcellular Localization Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}.
Disease Associations
Tissue Specificity Mainly detected in brain and kidney. {ECO:0000269PubMed:9756916}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008417 fucosyltransferase activity
GO:0046920 alpha-(1->3)-fucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0007399 nervous system development
GO:0036065 fucosylation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID MGI:1330859
InterPro IPR001503 Glycosyl transferase, family 10
PFAM PF00852
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88819
PhosphoSite PhosphoSite-
TrEMBL Q14AE3
UniProt Splice Variant
Entrez Gene 14348
UniGene Mm.414085
RefSeq
MGI ID
MGI Symbol Fut9
OMIM
CCDS CCDS18011
HPRD
IMGT
EMBL AB015426 AK032177 AK036183 AK043410 AK047650 AK049122 AK163871 BC116874 BC116876 CH466538
GenPept AAI16875 AAI16877 BAA33522 BAC27746 BAC29338 BAC31540 BAC33112 BAC33555 BAE37522 EDL05524

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca