InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptrh2

Summary

InnateDB Protein

IDBP-265421.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ptrh2

Protein Name

peptidyl-tRNA hydrolase 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103657

InnateDB Gene

IDBG-206996 (Ptrh2)

Protein Structure

UniProt Annotation

Function

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004045	aminoacyl-tRNA hydrolase activity
GO:0005515	protein binding

Biological Process

GO:0008152	metabolic process
GO:0010629	negative regulation of gene expression
GO:2000210	positive regulation of anoikis
GO:2000811	negative regulation of anoikis

Cellular Component

GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:2444848

InterPro

IPR002833 Peptidyl-tRNA hydrolase, PTH2
IPR023476 Peptidyl-tRNA hydrolase II domain

PFAM

PF01981

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8R2Y8

PhosphoSite

PhosphoSite-Q8R2Y8

TrEMBL

UniProt Splice Variant

Entrez Gene

217057

UniGene

RefSeq

NP_001092280

MGI ID

MGI Symbol

Ptrh2

OMIM

CCDS

CCDS48876

HPRD

IMGT

EMBL

AK028555 AK031620 AK038888 BC026947

GenPept

AAH26947 BAC26006 BAC27482 BAC30159