InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mbtd1

Summary

InnateDB Protein

IDBP-265782.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mbtd1

Protein Name

mbt domain containing 1

Synonyms

AA408199; AI194990; hemp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103486

InnateDB Gene

IDBG-208480 (Mbtd1)

Protein Structure

UniProt Annotation

Function

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4 (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008270	zinc ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016568	chromatin modification
GO:0048706	embryonic skeletal system development