InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Frmpd1

Summary

InnateDB Protein

IDBP-265892.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Frmpd1

Protein Name

FERM and PDZ domain containing 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000103434

InnateDB Gene

IDBG-143950 (Frmpd1)

Protein Structure

UniProt Annotation

Function

Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Found both in the cytoplasm and associated with the cell membrane. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0008150	biological_process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2446274

InterPro

IPR000159 Ras-association
IPR000299 FERM domain
IPR001478 PDZ domain
IPR018979 FERM, N-terminal
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR029071 Ubiquitin-related domain

PFAM

PF00788
PF00595
PF13180
PF09379
PF00373

PRINTS

PIRSF

SMART

SM00314
SM00228
SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2AKB4