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InnateDB Protein
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IDBP-266488.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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1110054O05Rik
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Protein Name
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RIKEN cDNA 1110054O05 gene
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Synonyms
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1110054O05Rik; 2610312O17Rik; AA399876; Ssbip1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000103150
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InnateDB Gene
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IDBG-151697 (1110054O05Rik)
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Protein Structure
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| Function |
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single- stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination- dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Nucleus {ECO:0000250}. Note=Localizes to nuclear foci following DNA damage. {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
2
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
6 [view]
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| PDB ID |
MGI:1913459
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
Z4YLT1
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| UniProt Splice Variant |
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| Entrez Gene |
66209
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| UniGene |
Mm.51988
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Inip
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL806512
AL929501
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| GenPept |
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Version 5.4