InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SYT10

Summary

InnateDB Protein

IDBP-26652.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SYT10

Protein Name

synaptotagmin X

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000228567

InnateDB Gene

IDBG-26650 (SYT10)

Protein Structure

UniProt Annotation

Function

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. {ECO:0000250}.

Subcellular Localization

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed only in pancreas, lung and kidney. {ECO:0000269PubMed:14756426}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0046982	protein heterodimerization activity