InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab13

Summary

InnateDB Protein

IDBP-266808.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Rab13

Protein Name

RAB13, member RAS oncogene family

Synonyms

0610007N03Rik; B230212B15Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102996

InnateDB Gene

IDBG-166105 (Rab13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0034236	protein kinase A catalytic subunit binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0010737	protein kinase A signaling
GO:0015031	protein transport
GO:0030866	cortical actin cytoskeleton organization
GO:0031175	neuron projection development
GO:0032456	endocytic recycling
GO:0032869	cellular response to insulin stimulus
GO:0070830	tight junction assembly
GO:0090002	establishment of protein localization to plasma membrane
GO:0097368	establishment of Sertoli cell barrier

Cellular Component

GO:0005622	intracellular
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0005911	cell-cell junction
GO:0005923	tight junction
GO:0016020	membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0016328	lateral plasma membrane
GO:0019897	extrinsic component of plasma membrane
GO:0030139	endocytic vesicle
GO:0032593	insulin-responsive compartment
GO:0043005	neuron projection
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:1927232

InterPro

IPR001806 Small GTPase superfamily
IPR003579 Small GTPase superfamily, Rab type
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF00025
PF08477

PRINTS

PR00449
PR00328

PIRSF

SMART

SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt