InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pip5k1a

Summary

InnateDB Protein

IDBP-267109.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pip5k1a

Protein Name

phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha

Synonyms

PI4P5K-I[a]; PIP5K1-alpha; PIP5KIalpha; Pipk5a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102852

InnateDB Gene

IDBG-171304 (Pip5k1a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016307	phosphatidylinositol phosphate kinase activity
GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0019900	kinase binding

Biological Process

GO:0008654	phospholipid biosynthetic process
GO:0010761	fibroblast migration
GO:0031532	actin cytoskeleton reorganization
GO:0032863	activation of Rac GTPase activity
GO:0046488	phosphatidylinositol metabolic process
GO:0046854	phosphatidylinositol phosphorylation
GO:0048041	focal adhesion assembly
GO:0060326	cell chemotaxis
GO:0072661	protein targeting to plasma membrane
GO:0097178	ruffle assembly

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
GO:0005886	plasma membrane
GO:0016607	nuclear speck
GO:0030027	lamellipodium
GO:0032587	ruffle membrane