InnateDB Protein
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IDBP-267174.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cdc42se1
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Protein Name
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CDC42 small effector 1
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Synonyms
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1300002M12Rik; AW558204; Cdcse1; SCIP1; Spec1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000102819
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InnateDB Gene
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IDBG-172007 (Cdc42se1)
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Protein Structure
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Function |
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1889510
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InterPro |
IPR000095
CRIB domain
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PFAM |
PF00786
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PRINTS |
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PIRSF |
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SMART |
SM00285
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BHL7
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PhosphoSite |
PhosphoSite-Q8BHL7
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TrEMBL |
D3YUZ5
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UniProt Splice Variant |
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Entrez Gene |
57912
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UniGene |
Mm.398797
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RefSeq |
NP_001033797
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MGI ID |
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MGI Symbol |
Cdc42se1
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OMIM |
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CCDS |
CCDS38545
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HPRD |
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IMGT |
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EMBL |
AC140190
AK004859
AK019052
AK028573
BC060964
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GenPept |
AAH60964
BAC25099
BAC25576
BAC26014
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