InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Plaa

Summary

InnateDB Protein

IDBP-267372.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Plaa

Protein Name

phospholipase A2, activating protein

Synonyms

2410007N06; AI536418; AU018445; AW208417; D4Ertd618e; PLA2P; PLAP; Ufd3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102724

InnateDB Gene

IDBG-163417 (Plaa)

Protein Structure

UniProt Annotation

Function

Involved in the maintenance of ubiquitin levels. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0016005	phospholipase A2 activator activity

Biological Process

GO:0006954	inflammatory response
GO:0043085	positive regulation of catalytic activity

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:104810

InterPro

IPR001680 WD40 repeat
IPR013535 PUL
IPR015155 PLAA family ubiquitin binding, PFU
IPR016024 Armadillo-type fold
IPR017986 WD40-repeat-containing domain

PFAM

PF00400
PF08324
PF09070

PRINTS

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P27612