InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fmo5

Summary

InnateDB Protein

IDBP-267504.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fmo5

Protein Name

flavin containing monooxygenase 5

Synonyms

5033418D19Rik; AI195026;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102665

InnateDB Gene

IDBG-177042 (Fmo5)

Protein Structure

UniProt Annotation

Function

In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. {ECO:0000250}.

Subcellular Localization

Microsome membrane. Endoplasmic reticulum membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0016491	oxidoreductase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1310004

InterPro

IPR000960 Flavin monooxygenase FMO
IPR002253 Flavin monooxygenase (FMO) 1
IPR002254 Flavin monooxygenase (FMO) 2
IPR002257 Flavin monooxygenase (FMO) 5
IPR012143 Dimethylaniline monooxygenase, N-oxide-forming
IPR020946 Flavin monooxygenase-like
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM

PF00743
PF07992

PRINTS

PR00370
PR01121
PR01122
PR01125

PIRSF

PIRSF000332

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt