Mus musculus Protein: Sppl2c | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-267603.7 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Sppl2c | ||||||||
Protein Name | RIKEN cDNA 4933407P14 gene | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000102613 | ||||||||
InnateDB Gene | IDBG-213105 (Sppl2c) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000250}. | ||||||||
Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | |||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:3045264 | ||||||||
InterPro |
IPR003137
Protease-associated domain, PA IPR006639 Presenilin/signal peptide peptidase IPR007369 Peptidase A22B, signal peptide peptidase |
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PFAM |
PF02225
PF04258 |
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PRINTS | |||||||||
PIRSF | |||||||||
SMART |
SM00730
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | A2A6C4 | ||||||||
PhosphoSite | PhosphoSite-A2A6C4 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 237958 | ||||||||
UniGene | Mm.117063 | ||||||||
RefSeq | NP_950184 | ||||||||
MGI ID | |||||||||
MGI Symbol | Sppl2c | ||||||||
OMIM | |||||||||
CCDS | CCDS36352 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AK077122 AL596383 BC100418 | ||||||||
GenPept | AAI00419 BAC36625 CAM21649 | ||||||||