Version 5.4
Mus musculus Protein: Trim45
Summary
InnateDB Protein IDBP-267638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trim45
Protein Name tripartite motif-containing 45
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000102593
InnateDB Gene IDBG-179366 (Trim45)
Protein Structure
UniProt Annotation
Function May act as a transcriptional repressor in mitogen- activated protein kinase signaling pathway.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0060348 bone development
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1918187
InterPro IPR000315 Zinc finger, B-box
IPR001298 Filamin/ABP280 repeat
IPR001841 Zinc finger, RING-type
IPR003649 B-box, C-terminal
IPR014756 Immunoglobulin E-set
IPR017868 Filamin/ABP280 repeat-like
PFAM PF00643
PF13639
PF14634
PF00630
PRINTS
PIRSF
SMART SM00336
SM00557
SM00184
SM00502
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PFY8
PhosphoSite PhosphoSite-Q6PFY8
TrEMBL
UniProt Splice Variant
Entrez Gene 229644
UniGene Mm.189351
RefSeq NP_001159424
MGI ID
MGI Symbol Trim45
OMIM
CCDS CCDS17678
HPRD
IMGT
EMBL AK076600 AK150574 AK153571 AL669872 BC057358
GenPept AAH57358 BAC36409 BAE29669 BAE32104 CAM22066

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca