InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gna13

Summary

InnateDB Protein

IDBP-268229.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Gna13

Protein Name

guanine nucleotide binding protein, alpha 13

Synonyms

AU024132; AU043124; Galpha13;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102313

InnateDB Gene

IDBG-213793 (Gna13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0031702	type 1 angiotensin receptor binding
GO:0031752	D5 dopamine receptor binding

Biological Process

GO:0001525	angiogenesis
GO:0001569	patterning of blood vessels
GO:0001701	in utero embryonic development
GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007266	Rho protein signal transduction
GO:0008360	regulation of cell shape
GO:0030154	cell differentiation
GO:0030168	platelet activation
GO:0030334	regulation of cell migration
GO:0031584	activation of phospholipase D activity
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005834	heterotrimeric G-protein complex
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
GO:0031526	brush border membrane

Protein Structure and Domains

PDB ID

MGI:95768

InterPro

IPR000469 G-protein alpha subunit, group 12
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR011025 G protein alpha subunit, helical insertion
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00503

PRINTS

PR00440
PR00318

PIRSF

SMART

SM00275

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt