Version 5.4
Mus musculus Protein: Arsg
Summary
InnateDB Protein IDBP-268241.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arsg
Protein Name arylsulfatase G
Synonyms 6330406P08Rik; AI846872;
Species Mus musculus
Ensembl Protein ENSMUSP00000102308
InnateDB Gene IDBG-213826 (Arsg)
Protein Structure
UniProt Annotation
Function Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate. {ECO:0000250}.
Subcellular Localization Lysosome. Note=Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004065 arylsulfatase activity
GO:0008484 sulfuric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006790 sulfur compound metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID MGI:1921258
InterPro IPR000917 Sulfatase
IPR017850 Alkaline-phosphatase-like, core domain
PFAM PF00884
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3TYD4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 74008
UniGene Mm.482224
RefSeq XP_006534410
MGI ID
MGI Symbol Arsg
OMIM
CCDS CCDS25581
HPRD
IMGT
EMBL AK018132 AK158726 AK173082 AL645791 BC022158 BC039629 BC084731 BN000747
GenPept AAH22158 AAH39629 AAH84731 BAB31086 BAD32360 BAE34629 CAI84993 CAM25215 CAM25216

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca