Version 5.4
Mus musculus Protein: Rnf141
Summary
InnateDB Protein IDBP-268274.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf141
Protein Name ring finger protein 141
Synonyms 2610110L04Rik; AA792898; AU022812; ZFP36; ZNF230;
Species Mus musculus
Ensembl Protein ENSMUSP00000102293
InnateDB Gene IDBG-206681 (Rnf141)
Protein Structure
UniProt Annotation
Function May be involved in spermatogenesis. {ECO:0000269PubMed:12804569}.
Subcellular Localization
Disease Associations
Tissue Specificity Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney, pancreas, lung, liver and testis. Isoform 3 is expressed in heart, liver, and kidney. {ECO:0000269PubMed:12804569}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1914400
InterPro IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF00097
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99MB7
PhosphoSite PhosphoSite-Q99MB7
TrEMBL H3BKH1
UniProt Splice Variant
Entrez Gene 67150
UniGene Mm.486738
RefSeq XP_006508186
MGI ID
MGI Symbol Rnf141
OMIM
CCDS CCDS40086
HPRD
IMGT
EMBL AC122844 AC184052 AF353167 AK006791 AK011839 AK015505 BC018553 CH466531
GenPept AAH18553 AAK31205 BAB24742 BAB27871 BAB29874 EDL16993 EDL16994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca