InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: 5330417C22Rik

Summary

InnateDB Protein

IDBP-268378.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

5330417C22Rik

Protein Name

RIKEN cDNA 5330417C22 gene

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102236

InnateDB Gene

IDBG-187475 (5330417C22Rik)

Protein Structure

UniProt Annotation

Function

May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Late endosome membrane {ECO:0000250}; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein. Lysosome membrane {ECO:0000250}; Single- pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding

Biological Process

GO:0009267	cellular response to starvation
GO:0016236	macroautophagy
GO:0044090	positive regulation of vacuole organization
GO:2000786	positive regulation of autophagic vacuole assembly
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005770	late endosome
GO:0005802	trans-Golgi network
GO:0005887	integral component of plasma membrane
GO:0031902	late endosome membrane
GO:0070062	extracellular vesicular exosome