Version 5.4
Mus musculus Protein: Cd300lb
Summary
InnateDB Protein IDBP-268472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd300lb
Protein Name CD300 antigen like family member B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000102191
InnateDB Gene IDBG-214156 (Cd300lb)
Protein Structure
UniProt Annotation
Function Acts as an activating immune receptor in mast cells through its interaction with ITAM-bearing adapter TYROBP. {ECO:0000269PubMed:17928527}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:17928527}; Single-pass type I membrane protein {ECO:0000269PubMed:17928527}.
Disease Associations
Tissue Specificity Expressed in myeloid cells (at protein level). {ECO:0000269PubMed:17928527}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002446 neutrophil mediated immunity
GO:0033005 positive regulation of mast cell activation
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2685099
InterPro IPR003599 Immunoglobulin subtype
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U497
PhosphoSite PhosphoSite-Q3U497
TrEMBL Q3TEQ8
UniProt Splice Variant
Entrez Gene 217304
UniGene Mm.185355
RefSeq
MGI ID
MGI Symbol Cd300lb
OMIM
CCDS
HPRD
IMGT
EMBL AB300703 AK154359 AK169466 AK170613 AL607025 AL669969 AY457053 AY996128 BC107351
GenPept AAR27944 AAY56360 BAE32536 BAE41190 BAE41912 BAF56590 CAM18752 CAM21172

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca