InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mast2

Summary

InnateDB Protein

IDBP-268670.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mast2

Protein Name

microtubule associated serine/threonine kinase 2

Synonyms

MAST205; Mtssk;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000102094

InnateDB Gene

IDBG-177819 (Mast2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0045075	regulation of interleukin-12 biosynthetic process

Cellular Component

GO:0015630

microtubule cytoskeleton

Protein Structure and Domains

PDB ID

MGI:894676

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001478 PDZ domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR015022 Microtubule-associated serine/threonine-protein kinase, domain
IPR020635 Tyrosine-protein kinase, catalytic domain
IPR023142 Microtubule-associated serine/threonine-protein kinase, pre-PK domain

PFAM

PF00069
PF07714
PF00595
PF13180
PF08926

PRINTS

PR00109

PIRSF

SMART

SM00228
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt