Version 5.4
Mus musculus Protein: Prpsap1
Summary
InnateDB Protein IDBP-268860.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prpsap1
Protein Name phosphoribosyl pyrophosphate synthetase-associated protein 1
Synonyms 5730409F23Rik; PAP39;
Species Mus musculus
Ensembl Protein ENSMUSP00000101999
InnateDB Gene IDBG-214464 (Prpsap1)
Protein Structure
UniProt Annotation
Function Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity
GO:0019900 kinase binding
GO:0030234 enzyme regulator activity
Biological Process
GO:0009165 nucleotide biosynthetic process
GO:0033673 negative regulation of kinase activity
Cellular Component
GO:0002189 ribose phosphate diphosphokinase complex
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:1915013
InterPro IPR005946 Ribose-phosphate diphosphokinase
IPR029057 Phosphoribosyltransferase-like
PFAM PF14572
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D0M1
PhosphoSite PhosphoSite-Q9D0M1
TrEMBL B1AT82
UniProt Splice Variant
Entrez Gene 67763
UniGene Mm.25125
RefSeq NP_080640
MGI ID
MGI Symbol Prpsap1
OMIM
CCDS CCDS48985
HPRD
IMGT
EMBL AK011290 AL645851 BC029621 CH466558
GenPept AAH29621 BAB27520 EDL34580

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca