Version 5.4
Homo sapiens Protein: FAM103A1
Summary
InnateDB Protein IDBP-26887.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM103A1
Protein Name family with sequence similarity 103, member A1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000307181
InnateDB Gene IDBG-26885 (FAM103A1)
Protein Structure
UniProt Annotation
Function Required for efficient mRNA cap methylation. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. {ECO:0000269PubMed:22099306}.
Subcellular Localization Nucleus {ECO:0000269PubMed:22099306}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006370 7-methylguanosine mRNA capping
GO:0032259 methylation
GO:0036031 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex
Cellular Component
GO:0005634 nucleus
GO:0005845 mRNA cap binding complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BTL3
PhosphoSite PhosphoSite-Q9BTL3
TrEMBL
UniProt Splice Variant
Entrez Gene 83640
UniGene Hs.80624
RefSeq NP_113640
HUGO HGNC:31022
OMIM 614547
CCDS CCDS10321
HPRD 12845
IMGT
EMBL BC003627 BC027181 BC112329
GenPept AAH03627 AAH27181 AAI12330

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca