InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cyp2u1

Summary

InnateDB Protein

IDBP-268979.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cyp2u1

Protein Name

cytochrome P450, family 2, subfamily u, polypeptide 1

Synonyms

8430436A10Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101944

InnateDB Gene

IDBG-194423 (Cyp2u1)

Protein Structure

UniProt Annotation

Function

Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed. {ECO:0000269PubMed:15752708}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0070330	aromatase activity

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1918769

InterPro

IPR001128 Cytochrome P450
IPR002397 Cytochrome P450, B-class
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV
IPR008069 Cytochrome P450, E-class, group I, CYP2D-like

PFAM

PF00067

PRINTS

PR00385
PR00359
PR00463
PR00465
PR01686

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CX98