InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fus

Summary

InnateDB Protein

IDBP-269157.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fus

Protein Name

fusion, derived from t(12;16) malignant liposarcoma (human)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101858

InnateDB Gene

IDBG-210494 (Fus)

Protein Structure

UniProt Annotation

Function

Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	81 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0042802	identical protein binding
GO:0044822	poly(A) RNA binding