Mus musculus Protein: Itgad | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-269191.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Itgad | ||||||
Protein Name | integrin, alpha D | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000101844 | ||||||
InnateDB Gene | IDBG-210571 (Itgad) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood- borne pathogens, particulate matter, and senescent erythrocytes from the blood (By similarity). {ECO:0000250}. | ||||||
Subcellular Localization | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. | ||||||
Disease Associations | |||||||
Tissue Specificity | |||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | MGI:3578624 | ||||||
InterPro |
IPR000413
Integrin alpha chain IPR002035 von Willebrand factor, type A IPR013517 FG-GAP repeat IPR013519 Integrin alpha beta-propellor IPR013649 Integrin alpha-2 IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved site |
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PFAM |
PF00092
PF01839 PF14312 PF08441 PF00357 |
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PRINTS |
PR01185
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PIRSF | |||||||
SMART |
SM00327
SM00191 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q3V0T4 | ||||||
PhosphoSite | PhosphoSite-Q3V0T4 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 381924 | ||||||
UniGene | Mm.334257 | ||||||
RefSeq | |||||||
MGI ID | |||||||
MGI Symbol | Itgad | ||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AK132915 | ||||||
GenPept | BAE21419 | ||||||